邵婉莹1 朱新康1 戴俊君1 朱春平1,2*
1.赣南医科大学 2.赣州市人民医院消化内科
摘要(Abstract):
功能性胃肠病(Functional Gastrointestinal Disorders,FGIDs)是消化内科常见病征群,其病理机制涉及多因素相互作用。研究表明,该疾病与脑-肠轴失调、内脏高敏感性、肠道菌群紊乱等生理病理改变密切相关。FGIDs的治疗缺乏特异性方法,FGIDs的传统药物治疗主要是注重于调节肠道动力方面,常用药物包括解痉药、促胃肠动力药等。现在新兴的治疗领域,如神经调节剂、改善肠道菌群、认知行为干预及精神心理疗法等,试图通过改变微生物群、精神心理因素来缓解患者的临床症状;将来也可以适当考虑实行从单一症状控制向多种治疗方法联合使用,从而提高FGIDs的治疗效果。
关键词(KeyWords):
功能性胃肠病;脑-肠轴;肠道微生物
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